The Hershey-Chase Experiment

Part A

This is an image of a _____.

	red blood cell
	protist
	moneran
	bacterium
	phage

Correct

This is a T2 phage, a type of phage that infects E. coli.

Part B

Who demonstrated that DNA is the genetic material of the T2 phage?

	Franklin
	Hershey and Chase
	Darwin and Wallace
	Meselson and Stahl
	Watson and Crick

Correct

Hershey and Chase did a series of classic experiments demonstrating that DNA is the genetic material of the T2 phage.

Part C

The radioactive isotope ³²P labels the T2 phage's _____.

	head
	DNA
	base plate
	tail
	protein coat

Correct

The T2 phage consists of a protein coat and DNA. It is the DNA that contains P.

Part D

Hershey and Chase used _____ to radioactively label the T2 phage's proteins.

	92U
	35S
	32P
	14C
	222Ra

Correct

Hershey and Chase used radioactive sulfur to label the phage's proteins.

Part E

After allowing phages grown with bacteria in a medium that contained ³²P and ³⁵S, Hershey and Chase used a centrifuge to separate the phage ghosts from the infected cell. They then examined the infected cells and found that they contained _____, which demonstrated that _____ is the phage's genetic material.

	labeled DNA .... protein
	labeled DNA ... labeled protein
	labeled protein ... DNA
	labeled protein .... protein
	labeled DNA ... DNA

Correct

Since the phage DNA entered the infected cell, it makes sense that DNA is the genetic material.